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Simon C Robson Selected Research

Apyrase (ATP Diphosphatase)

7/2020Modulation of CD39 and Exogenous APT102 Correct Immune Dysfunction in Experimental Colitis and Crohn's Disease.
9/2017Expression of Ecto-nucleoside Triphosphate Diphosphohydrolases-2 and -3 in the Enteric Nervous System Affects Inflammation in Experimental Colitis and Crohn's Disease.
1/2015CD39 improves survival in microbial sepsis by attenuating systemic inflammation.
8/2014Optimizing human apyrase to treat arterial thrombosis and limit reperfusion injury without increasing bleeding risk.
6/2012Overexpression of NTPDase2 in gliomas promotes systemic inflammation and pulmonary injury.
5/2012P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice.
4/2010SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning.
8/2009Selective NTPDase2 expression modulates in vivo rat glioma growth.
10/2007CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury.
9/2007Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury.
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Simon C Robson Research Topics

Disease

52Inflammation (Inflammations)
01/2021 - 04/2002
35Neoplasms (Cancer)
01/2022 - 01/2007
18Reperfusion Injury
01/2022 - 03/2004
15Fibrosis (Cirrhosis)
01/2020 - 01/2008
14Thrombosis (Thrombus)
01/2021 - 04/2002
12Vascular System Injuries
03/2014 - 03/2004
11Colitis
11/2020 - 04/2005
10Ischemia
01/2014 - 03/2004
9Hypoxia (Hypoxemia)
07/2020 - 09/2003
7Liver Cirrhosis (Hepatic Cirrhosis)
10/2021 - 01/2016
7Sepsis (Septicemia)
10/2017 - 10/2008
7Thrombocytopenia (Thrombopenia)
09/2014 - 01/2005
6Crohn Disease (Crohn's Disease)
11/2020 - 05/2011
6Neoplasm Metastasis (Metastasis)
01/2020 - 06/2011
6Hepatitis
01/2019 - 09/2008
6Hepatocellular Carcinoma (Hepatoma)
01/2019 - 10/2012
6Myocardial Infarction
01/2018 - 11/2005
5Non-alcoholic Fatty Liver Disease
10/2021 - 01/2013
5Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
01/2019 - 04/2005
5Hemorrhage
09/2014 - 07/2003
4Pneumonia (Pneumonitis)
01/2021 - 01/2016
4Infections
01/2019 - 06/2003
4Infarction (Infarctions)
08/2014 - 10/2007
4Colonic Neoplasms (Colon Cancer)
04/2013 - 06/2007
3Insulin Resistance
03/2016 - 09/2008
3Pathologic Processes
01/2016 - 01/2005
3Lung Injury
12/2015 - 06/2012
3Thrombotic Microangiopathies
11/2015 - 07/2003
3Necrosis
03/2015 - 08/2008
3Myocardial Ischemia (Ischemic Heart Diseases)
01/2012 - 10/2007
2Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 04/2013
2Melanoma (Melanoma, Malignant)
01/2022 - 12/2012
2Graft vs Host Disease (Graft-Versus-Host Disease)
01/2021 - 01/2021
2Autoimmune Hepatitis
01/2021 - 06/2012
2Diabetic Nephropathies (Diabetic Nephropathy)
01/2018 - 09/2007

Drug/Important Bio-Agent (IBA)

34Adenosine (Adenocard)FDA LinkGeneric
01/2022 - 09/2003
34Adenosine Triphosphate (ATP)IBA
01/2022 - 04/2002
25NucleotidesIBA
01/2021 - 04/2002
14triphosphoric acid (triphosphate)IBA
01/2021 - 04/2002
12Adenosine Diphosphate (ADP)IBA
10/2021 - 04/2002
12NucleosidesIBA
12/2018 - 04/2002
11Apyrase (ATP Diphosphatase)IBA
07/2020 - 03/2004
11EnzymesIBA
01/2018 - 12/2008
9Purinergic Receptors (Receptors, Purine)IBA
01/2021 - 11/2006
9CytokinesIBA
01/2020 - 01/2008
9Proteins (Proteins, Gene)FDA Link
01/2017 - 06/2003
7ectoATPaseIBA
08/2020 - 03/2006
7Messenger RNA (mRNA)IBA
01/2016 - 09/2003
65'-Nucleotidase (5' Nucleotidase)IBA
01/2022 - 12/2004
6Biological ProductsIBA
01/2022 - 01/2005
6CD39 antigenIBA
10/2021 - 10/2007
6Dextran SulfateIBA
07/2020 - 11/2005
6Purinergic P1 Receptors (Adenosine Receptor)IBA
01/2019 - 11/2006
5Adenosine Monophosphate (AMP)IBA
10/2021 - 12/2004
5Oxygen (Dioxygen)IBA
01/2021 - 09/2003
5SodiumIBA
01/2019 - 05/2011
5Biomarkers (Surrogate Marker)IBA
07/2018 - 10/2011
4Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2021 - 06/2015
4InflammasomesIBA
01/2020 - 01/2014
4MicroRNAs (MicroRNA)IBA
07/2018 - 10/2012
4Interleukin-10 (Interleukin 10)IBA
01/2018 - 08/2008
4Dextrans (Dextran)FDA Link
09/2017 - 04/2005
4Pharmaceutical PreparationsIBA
01/2017 - 04/2008
4Adenine NucleotidesIBA
01/2016 - 09/2003
3Adenosine DeaminaseIBA
10/2021 - 10/2014
3beta-apocarotenoid-14',13'-dioxygenase (ADO)IBA
10/2021 - 07/2012
3Therapeutic UsesIBA
07/2020 - 01/2018
3CollagenIBA
01/2019 - 01/2008
3purineIBA
01/2019 - 12/2008
33,5- diethoxycarbonyl- 1,4- dihydrocollidineIBA
01/2019 - 11/2017
3Thromboplastin (Tissue Factor)IBA
01/2018 - 04/2006
3LipidsIBA
01/2018 - 01/2013
3Purinergic P2X7 ReceptorsIBA
10/2017 - 05/2013
3AnticoagulantsIBA
05/2017 - 11/2005
3Blood Coagulation Factors (Coagulation Factor)IBA
05/2017 - 06/2003
3VLDL LipoproteinsIBA
03/2016 - 01/2013
3Lipoproteins (Lipoprotein)IBA
01/2016 - 01/2013
3Triglycerides (Triacylglycerol)IBA
01/2014 - 06/2010
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
04/2013 - 10/2008
3Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
10/2012 - 07/2003
2Interleukin-27 (Interleukin 27)IBA
01/2022 - 10/2013
2PurinesIBA
01/2021 - 01/2020
2Sulfonic AcidsIBA
11/2020 - 05/2011
2Deferoxamine (Desferal)FDA LinkGeneric
07/2020 - 04/2005
2Interleukin-2 (IL2)IBA
01/2020 - 01/2019
2Purinergic P1 Receptor AntagonistsIBA
01/2019 - 07/2012
2LigandsIBA
11/2018 - 09/2017
2BilirubinIBA
11/2018 - 05/2017
2AngiopoietinsIBA
07/2018 - 07/2016
2SaltsIBA
01/2018 - 07/2012

Therapy/Procedure

24Therapeutics
01/2022 - 07/2003
12Transplantation
01/2021 - 05/2004
8Heterologous Transplantation (Xenotransplantation)
01/2022 - 06/2003
6Liver Transplantation
01/2019 - 11/2005
4Drug Therapy (Chemotherapy)
01/2022 - 04/2008
4Ligation
11/2018 - 10/2008
3Immunotherapy
01/2022 - 01/2017
3Punctures
10/2017 - 10/2008
2Artificial Respiration (Mechanical Ventilation)
01/2021 - 12/2017
2Aftercare (After-Treatment)
01/2019 - 12/2015